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Fluorinated GlcNAc analogs are valuable probes for studying GlcNAc-processing enzymes (O-GlcNAc transferase / OGA
β-D-(Galβ1-4Glc)-O-(CH2)2-SH
Ashwell-Morell receptor)
96 / Synthetic glycopeptide fragment (Thr1179-Asp1194
C21H36N2O14 / 540
PE131020: β-GalNAc-PEG3-DBCO Pack Size:2.5 mg Fluorinated GlcNAc analogs are valuableC33H41N3O10 639. 69 A D N acetylgalactosamine (GalNAc) ligand equipped with a dibenzocyclooctyne (DBCO) handle through a hydrophilic PEG3 spacer. The DBCO group reacts with azides via copper free strain promoted azide alkyne cycloaddition (SPAAC), forming stable 1,2,3 triazole linkages without a copper catalyst. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor
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